RNF2 E3 or Not to E3: Dual Roles of RNF2 Overexpression in Melanoma
نویسندگان
چکیده
منابع مشابه
RNF2 E3 or Not to E3: Dual Roles of RNF2 Overexpression in Melanoma.
RNF2/RING1B is amplified and overexpressed in numerous tumors and contributes to tumorigenicity; however, the biologic importance is poorly understood. Surprisingly, the role of RNF2 in tumorigenesis and invasion can be separated into catalytically independent and catalytically dependent processes.
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ژورنال
عنوان ژورنال: Cancer Discovery
سال: 2015
ISSN: 2159-8274,2159-8290
DOI: 10.1158/2159-8290.cd-15-1285